In the course of reading David Lapoujade’s Aberrant Movements, readers will undoubtedly encounter its overtly nuanced positioning. In relation to the existent patterns of critical engagement with Deleuze’s works, Lapoujade chooses to make his book seem like an expressive tissue of an expanding poetic universe rather than a measurable extensity from some representational whole. So the potency of his book, as Rajchman makes evident in the ‘Introduction’ to Aberrant Movements, doesn’t lie in unfolding like a teleological mimicry of what stands (...) before us as some kind of palimpsestic accretion of a-categorical Deleuzean readings. Rather his work is a perversely creative exercise in repeating these readings into openings of inassimilable differences. Such an inclusively ‘exclusive positioning’ of his book brings about what we may call a transformative de-familiarization of it, rendering it as indistinct patterns of aberrant movements that continuously and creatively shift us from one kind of complex territorial intensity to another. (shrink)

In recent years India has been moving further in the direction of adopting an Anglo-American model of corporate governance. This decision, the result more of international economic and political pressures than public debate, in effect represents a new development strategy for the world's most populous democracy. In light of this situation, it is important to ask two basic questions: 1) why has the Anglo-American model of corporate governance been adopted? and; 2) can it be justified? This paper addresses the first (...) of these questions by distinguish and examining three historical models of governance in India: 1) the managing agency model in the colonial period; 2) the business house model that emerged after independence, and; 3) the Anglo-American model which has recently been adopted (and is still emerging). The second question is approached through an examination of the "development impact" of the new model, as indicated by such measures as growth, employment and respect for shareholder rights. (shrink)

As social media becomes increasingly popular, human subjects researchers are able to use these platforms to locate, track, and communicate with study participants, thereby increasing participant retention and the generalizability and validity of research. The use of social media; however, raises novel ethical and regulatory issues that have received limited attention in the literature and federal regulations. We review research ethics and regulations and outline the implications for maintaining participant privacy, respecting participant autonomy, and promoting researcher transparency when using social (...) media to locate and track participants. We offer a rubric that can be used in future studies to determine ethical and regulation-consistent use of social media platforms and illustrate the rubric using our study team’s experience with Facebook. We also offer recommendations for both researchers and institutional review boards that emphasize the importance of well-described procedures for social media use as... (shrink)

I present a Third World critique of the trend in American environmentalism known as deep ecology, analyzing each of deep ecology’s central tenets: the distinction between anthropocentrism and biocentrism, the focus on wildemess preservation, the invocation of Eastem traditions, and the belief that it represents the most radical trend within environmentalism. I argue that the anthropocentrism/biocentrism distinction is of little use in understanding the dynamics of environmental degredation, that the implementation of the wildemess agenda is causing serious deprivation in the (...) Third World, that the deep ecologist’s interpretation of Eastem traditions is highly selective, and that in other cultural contexts radical environmentalism manifests itself quite differently, with a far greater emphasis on equity and the integration of ecological concems with livelihood and work. I conclude that despite its claims to universality, deep ecology is firmly rooted in American environmental and cultural history and is inappropriate when applied to the Third World. (shrink)

Coastal protection is crucial to human development since the ocean has many values associated with the economy, ecosystem, and culture. However, most ocean protecting efforts are currently ineffective due to the burdens of finance, lack of appropriate management, and international cooperation regimes. For aiding bottom-up initiatives for ocean protection support, this study employed the Mindsponge Theory to examine how the public’s perceived economic and cultural values influence their willingness to support actions to protect the ocean. Analyzing the European-Union-Horizon-2020-funded dataset of (...) 709 respondents from 42 countries, we discovered that perceived economic values have negative effects on the tendency of ocean protection supports (i.e., food, transportation, renewable energy, oil and gas, and recreation). In contrast, certain perceived cultural values can help increase the willingness to do so (i.e., mental well-being and sense of identity). However, the effects of perceived cultural values are only moderately reliable. These findings suggest that designing cultural information delivery campaigns can help promote coastal reserve supports, such as fundraisings and preserving the oceans from the community. (shrink)

This essay reads John Locke’s Two Treatises through its nonhuman animal presences, especially the emblematic figures of cattle and “noxious creatures” like “lyons,” “tygers,” and wolves. It argues that the real ground of Lockean human equality is an ongoing practice of subjugating nonhuman animals, and not any attribute of the human species as such. More specifically, the Lockean social compact founded on this equality relies on a “dominion covenant,” an existential “agreement” in which God lends the power of dominion to (...) man and any threats to this order require punishment. This dynamic enables violence toward humans, in the name of their humanity, if they do not properly exert their power of dominion. Critics have connected Locke’s theory of property to indigenous dispossession and his theory of punishment to carceral systems; both processes, I argue, intimately rely on the dominion covenant. Lockean racism is the fulfillment of, and not a deviation from, his account of human equality. (shrink)

Arthāpatti does not depend on observation of pervasion or background belief. It is certain in the sense that when S cognizes P through postulation, no other epistemic instrument would invalidate P. The Naiyāyika tries to reduce postulation to anumāna and/or tarka. I shall argue that it is neither. Due to its explanatory role, one may think that postulation plays an essential role in lakṣaṇā or indication. But this too is a misconception. Both tarka and lakṣaṇā depend on observation and background (...) knowledge. Neither of them has the epistemic certainty postulation enjoys. I think, due to its observation-independent nature and certainty, postulation can be seen as the source of the knowledge of the truths of reason. (shrink)

The meaning of the term ‘tarka’ is not clear in the modern literature on Classical Indian Philosophy. This paper will review different modern readings of this term and try to show that what the Nyāyasūtra and its classical commentaries called a ‘tarka’ should be understood as the following: a tarka is a cognitive act that validates a content (of a doubt or a cognition or a speech-act) by demonstrating its logical fitness or invalidates a content by demonstrating its logical unfitness. (...) A tarka can act as a metatheory too. Generating certainty is, according to the Classical Nyāya, a job assigned to an epistemic instrument ( pramāṇa ). It fails to do so when there arises a doubt regarding it. The moment a tarka dispels the doubt, the epistemic instrument generates certainty. Tarkas of different types will be exemplified by critically analyzing Gaṅgeśa’s applications of tarka in his magnum opus Tattvacintāmaṇi . These examples will clarify the definition of tarka formulated in this paper. (shrink)

The work of three present-day Sankritist-philosophers, _God and the World's Arrangement_ allows readers to engage directly with writings of the classical Indian philosophers Śaṅkara and Vācaspati, as well as some of their most acute critics, on the question of whether the existence of a creator God can be known by reason alone. Carefully selected and annotated with the needs of students foremost in mind, these new translations will be of interest to anyone wishing to see up close a newly set (...) gem of our philosophical inheritance from global antiquity. (shrink)

The strainer tests the strength of a definition of a particular kind. Suppose the definition D is stated in terms of an absence, and x is a definiendum of D. The strainer collects each x-token or x-individual that dissatisfies D in a specific case. Then, all the x-individuals put together would be equivalent to the type x. Hence—one would be forced to conclude that—in a sense, x dissatisfies D. This is a case of under-application of D, since, despite being a (...) definiendum of D, x dissatisfies D. Therefore, D would be too narrow. Similarly, the strainer may detect over-application too. By using the strainer, Raghunātha Śiromaṇi demonstrated that Gaṅgeśa’s conclusive definition of pervasion had a defect, and redefined pervasion. The strainer test is based on intuitive principles. It may disqualify a definition that has an absence in its definiens. Therefore, strainer-proofing becomes an important consideration that must be borne in mind every time we formulate such a definition. (shrink)

A mahāvidyā inference is used for establishing another inference. Its Reason is normally an omnipresent property. Its Target is defined in terms of a general feature that is satisfied by different properties in different cases. It assumes that there is no case that has the absence of its Target. The main defect of a mahāvidyā inference μ is a counterbalancing inference that can be formed by a little modification of μ. The discovery of its counterbalancing inference can invalidate such an (...) inference. This paper will argue that Cantor’s diagonal argument too shares some features of the mahāvidyā inference. A diagonal argument has a counterbalanced statement. Its main defect is its counterbalancing inference. Apart from presenting an epistemological perspective that explains the disquiet over Cantor’s proof, this paper would show that both the mahāvidyā and diagonal argument formally contain their own invalidators. (shrink)

When somebody speaks metaphorically, the primary meanings of their words cannot get semantically connected. Still metaphorical uses succeed in conveying the message of the speaker, since lakṣaṇā, a meaning-generating faculty of language, yields the suitable secondary meanings. Gaṅgeśa claims that lakṣaṇā is a faculty of words themselves. One may argue: “Words have no such faculty. In these cases, the hearer uses observation-based inference. They have observed that sometimes competent speakers use the word w in order to mean s, when p, (...) the primary meaning of w does not make any semantic sense. In all such cases, s is actually related to p. After having observed this, when the hearer hears the utterance of w, and realizes that w’s primary meaning p is semantically unfit for the sentence-meaning, they infer on the basis of their prior observation that ‘the competent speaker must mean s by uttering w’. Thus lakṣaṇā becomes a success.” This apparently well-argued reduction does not stand the critical examination; neither in Gaṅgeśa’s framework, nor even in the general theory of language. For one can compose and interpret potentially infinite novel sentences based on lakṣaṇā while the observational inferences one can make are finite. Gaṅgeśa says very clearly that as far as the secondary meaning is concerned, no prior observation is required. This paper will argue that not only does language yield secondary meanings through lakṣaṇā, but it also restricts the use of secondary meanings; for one cannot mean just anything by saying something. Lakṣaṇā is a creative function with infinite potential within the limits set up by the language faculty. (shrink)

How does one give voice to the unspeakable, inhuman violence that shapes the present, and what remains of humanity in its wake? Adriana Cavarero offers an answer that roots human speech in embodied vulnerability, in contrast to philosophical emphases on disembodied rationality. In the face of what she calls horrorism, which puts humans in proximity to animality, she calls for resuscitating vocality, and therefore humanity, from loss. This article reads Kafka’s short story “A Report to an Academy” – which structurally (...) resembles a slave narrative and concerns a kidnapped ape who learns to speak – to extend Cavarero’s emphasis on vulnerability while challenging her humanism. In Kafka, modern horror’s locus is not animality but the abstract human, and it projects the unstable distinction between voice and noise onto blackened humans and nonhuman animals. (shrink)

A mahāvidyā inference is used for establishing another inference. Its Reason is normally an omnipresent property. Its Target is defined in terms of a general feature that is satisfied by different properties in different cases. It assumes that there is no case that has the absence of its Target. The main defect of a mahāvidyā inference μ is a counterbalancing inference that can be formed by a little modification of μ. The discovery of its counterbalancing inference can invalidate such an (...) inference. This paper will argue that Cantor’s diagonal argument too shares some features of the mahāvidyā inference. A diagonal argument has a counterbalanced statement. Its main defect is its counterbalancing inference. Apart from presenting an epistemological perspective that explains the disquiet over Cantor’s proof, this paper would show that both the mahāvidyā and diagonal argument formally contain their own invalidators. (shrink)

A speaker utters the grammatically correct phrase ‘x y’, and the hearer understands its meaning. The Naiyāyika claims that the only epistemic instrument that generates the semantic connection between the meaning of x and the meaning of y is testimony. This connection is essentially the phrase-meaning. The Vaiśeṣika wants inference to generate this connection. After presenting the Vaiśeṣika view on this topic, this paper will argue that, the hearer considers the generic categories of |x| and |y|, and infers their ontic (...) relation which finally will figure in the testimonial cognition. For example, when John tells Smith that ‘Jones smokes’, Smith first cognizes the meanings of the words, i.e., the individual called Jones and the activity of smoking. Then Smith infers that ‘John intends to say that the activity of smoking inheres in Jones, since an activity inheres in an individual.’ Thus, inherence which appears as the sematic connection is inferred in this case. If John is a reliable speaker, Smith will have a piece of testimonial knowledge. This is how the Vaiśeṣika’s inference could possibly support linguistic creativity. (shrink)

Brahmānanda Sarasvatī has written an elaborate comment on the following inference cited in Advaitasiddhi: attribute etc. are identical to and different from attributee etc. since they are co-referential. There he wants to prove that every significant case of attribution is a case of identity that coexists with a difference between two demarcators. The identity that coexists with difference is called ‘equality’. This paper will argue that in each case of equality, the realist ontology chooses either identity over difference or the (...) reverse. In the case of ‘the black pot’, the realist ontology prefers difference over identity. In the case of ‘the qualified object is the mere object’, the same ontology prefers identity over difference. Accordingly the ontological ‘entity’ gets projected. This is perhaps because the realist ontology is guided by Ockham’s razor and the grammatical classification of objects. (shrink)

An absence and its locus are the same ontological entity. But the cognition of the absence is different from the cognition of the locus. The cognitive difference is caused by a query followed by a cognitive process of introspection. The moment one perceptually knows y that contains only one thing, z, one is in a position to conclude that y contains the absence of any non-z. After having a query as to whether y has x one revisits one’s knowledge of (...) y containing z and comes to know that x is absent from y. Thus the knowledge of the absence of x logically follows from the knowledge of y containing z through the mediation of a query. This analysis goes against the thesis according to which an absence is an irreducible entity that is to be known through senses, and is inspired by the Mīmāṃsā views, especially the Prābhākara views, on absence and its cognition. (shrink)

The volume documents, and makes an original contribution to, an astonishing period in twentieth-century philosophy—the progress of Arne Naess's ecophilosophy from its inception to the present. It includes Naess's most crucial polemics with leading thinkers, drawn from sources as diverse as scholarly articles, correspondence, TV interviews and unpublished exchanges. The book testifies to the skeptical and self-correcting aspects of Naess's vision, which has deepened and broadened to include third world and feminist perspectives. Philosophical Dialogues is an essential addition to the (...) literature on environmental philosophy. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:God and the World's Arrangement: Readings from Vedānta and Nyāya Philosophy of Religion by Nirmalya Guha, Matthew Dasti, and Stephen PhillipsSwami Narasimhananda (bio)God and the World's Arrangement: Readings from Vedānta and Nyāya Philosophy of Religion. Translated, with Introduction and Explanatory Notes, by Nirmalya Guha, Matthew Dasti, and Stephen Phillips. Indianapolis: Hackett, 2021. Pp. xx + 91. Paperback $19.00, isbn 978-1-62466-957-6.The scarcity of accessible English translations of (...) Sanskrit texts that retain the philosophical rigor of the original has been a great challenge in Indian philosophy. God and the World's Arrangement, a translation with introduction and explanatory notes by Nirmalya Guha, Matthew Dasti, and Stephen Phillips, is an example of how this scarcity could be addressed without straying away from present-day idioms and context. This book discusses the perspectives on God and the arrangement of the world according to Nyāya, Vedānta, Mīmāṃsā, and Buddhist philosophies. This book is divided into two parts, followed by two appendices, and a bibliography. Each part has study questions at the end and there is an impressive reading list. The first part is a translation and analysis of Śaṅkara's theistic argument in his commentary on the Brahma-sūtra 2.2.1–10. The translators also include the subcommentary by Vācaspati Miśra. The second part contains the translation and analysis of Vācaspati Miśra's theistic argument in his commentary on the Nyāya-sūtra 4.1.19–21. All translations are followed by explanations that elaborate the contexts of the arguments. The translations in this book are elegant and use modern English idioms.The seeds of this book were sown by a guest lecture by Nirmalya Guha to a philosophy course at the University of Texas at Austin. The other two authors joined hands with Guha and worked on texts from Sāṃkhya, Nyāya, Vedānta, and Buddhist schools of thought. Scholars around the world are now interested in having a pan-global view of philosophy. However, such an understanding requires an informed engagement with the various contexts and mores of thought. This deceptively slim volume addresses this problem by succinctly providing the required background context and clarifying many commonly held misconceptions about Indian philosophy, particularly Advaita Vedānta. For a long time, there have not been many serious readings of Advaita Vedānta texts. This book comes as a relief and explains the basic concepts of Advaita Vedānta with readings from relevant portions of texts like the Brahma-sūtra. This book is a step to fill the gap [End Page 1] of texts that properly voice the perspectives of scholars from within the traditions following Advaita Vedānta.It is heartening to read a contemporary text that acknowledges the unbiased masterly exegetical work of Vācaspati Miśra that earned him the epithet sarva-tantra-svatantra, "one who is equally proficient in all the disciplines of knowledge." The translators and editors of this book have a noble goal of "coupling Vācaspati's works on Vedānta and on Nyāya" to make "it possible for a wide swath of his work to be pondered, little of which is currently accessible despite Vācaspati's importance for the whole of classical Indian philosophical thought" (p. xi). The editors lose no time in clarifying the approach of the texts explained in the book from Vedānta and Nyāya philosophies. They explain in some detail one of the means of knowledge, pramāṇa s, used by the Indian philosophies that adhere to the Vedās, the means of anumāṇa or inference. An interesting aspect of this book is the contemporary examples that the translators give, like those of a politician and automobile manufacturers. For instance, the translators explain different ways in which arguments given through an example can fail. The translators explain the error of an example not having the property to be proved in this manner:Yet another type of failure occurs when the property to be proved is not actually present in the example. Should one argue that "People who purchase Japanese vehicles... (shrink)

This review discussion examines two recent works on Gandhi, Richard Sorabji’s Gandhi and the Stoics: Modern Experiments on Ancient Values, and Ram Guha’s Gandhi Before India. The review makes the point that we can see Gandhi’s unusual philosophical method at work if the two books are read together. Sorabji has argued that it is essential to understand Gandhi’s philosophy before we can assess the consistency between what he thought, believed and did. Guha has recorded events in Gandhi’s early (...) years that can provide readers with details of Gandhi’s practise and experiments. (shrink)

This is a review of Guh'as magnum opus which honestly problematises Tagore's Mussolini episode.

In lieu of an abstract, here is a brief excerpt of the content:Ethics & the Environment 8.2 (2003) 132-139 [Access article in PDF] Environmentalism: A Global History, by Ramachandra Guha. New York: Longman, 161 pp, includes Bibliographic Essay and Index. Softcover, ISBN 0-321-01169-4. This short but wide-ranging book is a global survey of the history of environmental thought by one of the people most responsible for broadening environmental discussions to include recognition of post-colonial societies. The overall goal of this (...) introductory textbook is to explain multiple environmental discourses from Brazil, the United States, China, India, the Soviet Union, and Africa, and then to situate them as complimentary components of a global socially oriented environmental discursive framework.With that said, it is always difficult to evaluate an introductory textbook. In this case, much of what is covered represents well-worn ground for the environmental scholar. The thesis that emerges is less about a new set of environmental proposals and more about how we ought to understand the history of ideas that informs the development of policy and what ideas ought to be taught in the classroom. Since this book is designed as a textbook, much of my commentary stems from a consideration of how it might work in the classroom. [End Page 132]As an educator regularly teaching courses in environmental thought, ethics, planning, and policy, I have often wondered why so few texts exist on the global history of environmental thought. Guha's work represents an attempt to bridge this gap in the literature. Despite Guha's admirable intentions, I am hesitant to endorse this work as an introductory textbook on the global history of environmental thought for one important reason: Guha's methodology leads to the omission of important components of the global history of environmental thought. From the outset, it is important to acknowledge the difficulty of this type of project. The very title of this work signals perhaps an impossible project, given the 145 pages of text set aside for the task. Guha does cover a number of subjects well, and some are welcome additions to the discussion of the history of environmental thought. Overall though, the topics not covered work to neutralize what is accomplished by the topics that are covered. Consider first what Guha does include.The book is divided into two parts, each focusing on a wave of environmental thought. In the first part, there are four chapters and an afterword. In the initial chapter, Guha argues that a more social and international environmentalism can be a spur to "human reflection and human action," and not just a "scientific study of the state of nature or a balance sheet of the impact of human beings on the earth" (p. 3). While it is common to divide the environmental movement into waves (usually three or four), Guha chooses to delineate only one major shift and thus only two waves of environmentalism. The first wave is comprised of what Guha calls a "period of pioneering and prophecy" and an initial reaction to industrialization; the second wave is comprised of the more socially oriented responses that have emerged in recent decades (p. 3). There are good reasons for delineating more waves, but Guha's project is generally well-served by the two-wave distinction.Guha divides the first wave into three varieties distinguished by their different guiding ideologies—back-to-the-land, scientific conservation, wilderness idea—which are treated respectively in chapters two, three, and four. What I found most compelling about Guha's varieties are some of the figures he chose to include. For example, in chapter two Guha offers a treatment of the back-to-the-land ideology that concurrently condemned excessive industrialization and espoused a commitment to agrarian and pastoral values. From William Wordsworth, William Blake, John Clare, Edward Carpenter, Henry David Thoreau, John Ruskin, Edward Carpenter, [End Page 133] Henry David Thoreau, William Morris, and Octavia Hill, to Gandhi and the Nazis, Guha's range here is impressive. While I do have reservations about how convincing it is to link Wordsworth, Ruskin, and Gandhi according to a largely generic and nondescript agrarian ideal that he claims... (shrink)

Over the last two decades there has been a proliferation of partnerships between business and government, multilateral bodies, and/or social actors such as NGOs and local community organizations engaged in promoting development. While proponents hail these partnerships as an important new approach to engaging business, critics argue that they are not only generally ineffective but also serve to legitimate a neo-liberal, global economic order which inhibits development. In order to understand and evaluate the role of such partnerships, it is necessary (...) to appreciate their diversity with respect to not only the activities that they engage in, but also the degree to which they are subject to social control. This paper distinguishes four different types of business partnerships, based upon differing degrees of social control: conventional business; corporate social responsibility; corporate accountability; and social economy. Each type of partnership is described, their basic forms are noted, and the conditions and prospects for them contributing to development are examined. By way of conclusion, an analysis is offered of how the different types of business partnerships relate to different conceptions of development and function as policy paradigms to promote different globalization agendas. (shrink)

The motivation of someone who is locked-in, that is, paralyzed and mute, is to find relief for their loss of function. The data presented in this report is part of an attempt to restore one of those lost functions, namely, speech. An essential feature of the development of a speech prosthesis is optimal decoding of patterns of recorded neural signals during silent or covert speech, that is, speaking “inside the head” with output that is inaudible due to the paralysis of (...) the articulators. The aim of this paper is to illustrate the importance of both fast and slow single unit firings recorded from an individual with locked-in syndrome and from an intact participant speaking silently. Long duration electrodes were implanted in the motor speech cortex for up to 13 years in the locked-in participant. The data herein provide evidence that slow firing single units are essential for optimal decoding accuracy. Additional evidence indicates that slow firing single units can be conditioned in the locked-in participant 5 years after implantation, further supporting their role in decoding. (shrink)

This is a broad overview of how the prevalent family systems in the developing world influence sex preference for children. Son preference is evident in the data in East Asia and South Asia, and in the Middle East and North Africa, where patriarchal family systems make sons more valuable than daughters to parents in terms of economic, physical, and emotional sustenance. In sub-Saharan Africa, Latin America and Southeast Asia, there is little difference between the levels of support parents can expect (...) from sons and daughters—and little revealed sex preference in the data. (shrink)

Zygon®, Volume 57, Issue 3, Page 826-828, September 2022.

Philosophy & Social Criticism, Volume 48, Issue 4, Page 590-602, May 2022.

Philosophy & Social Criticism, Ahead of Print.

Philosophy & Social Criticism, Volume 48, Issue 4, Page 590-602, May 2022.

Philosophy & Social Criticism, Volume 48, Issue 4, Page 590-602, May 2022.

Philosophy & Social Criticism, Ahead of Print.

In an attempt to explore further the Madelung fluid-like representation of quantum mechanics, we derive the small perturbation equations of the fluid with respect to its basic states. The latter are obtained from the Madelung transform of the Schrödinger equation eigenstates. The fundamental eigenstates of de Broglie monochromatic matter waves are then shown to be mapped into the simple basic states of a fluid with constant density and velocity, where the latter is the de Broglie group velocity. The normal modes (...) with respect to these basic states are derived and found to also satisfy the de Broglie dispersion relation. Despite being dispersive waves, their propagation mechanism is equivalent to that of sound waves in a classical ideal adiabatic gas. We discuss the physical interpretation of these results. (shrink)

This textbook for postgraduate students learning mathematical methods in economics provides a comprehensive account of mathematics required to analyse and solve problems of choice encountered by economists. It looks at a wide variety of decision-making problems, both static and dynamic, in various contexts and provides mathematical foundations for the relevant economic theory.

Media Ethics has been designed as a textbook for under- and post-graduate students of Mass Communication and Journalism courses. It discusses key ethical issues in the light of the new face of journalism and the dynamic changes that are taking place in media today.

Since the onset of the COVID-19 pandemic, a controversial criterion for allocating scarce medical treatment has been defended and incorporated into policy: the criterion of equity. Equity-included allocation schemes prioritize, to some degree, patients from marginalized or historically disadvantaged racial/ethnic groups, or patients with low socioeconomic status, for scarce treatment. The use of such criteria has been most prominently defended in two ways: (1) as reflecting a risk factor for severe COVID-19, and thus as a way of tracking medical need, (...) and (2) as a form of remedial justice, viz. a way of redressing disparities in COVID outcomes that are caused by underlying unjust social conditions. Here, we delineate and critique those arguments. We argue that not only are such arguments unconvincing but also that there are compelling moral reasons to reject the sort of equity-included allocation schemes at issue. (shrink)

Once regarded as cellular ‘debris’ extracellular vesicles (EVs) emerge as one of the most intriguing entities in cancer pathogenesis. Intercellular trafficking of EVs challenges the notion of cancer cell autonomy, and highlights the multicellular nature of such fundamental processes as stem cell niche formation, tumour stroma generation, angiogenesis, inflammation or immunity. Recent studies reveal that intercellular exchange mediated by EVs runs deeper than expected, and includes molecules causative for cancer progression, such as oncogenes (epidermal growth factor receptor, Ras), and tumour (...) suppressors (PTEN). The uptake of oncogenic EVs (oncosomes) by various cells may profoundly change their biology, signalling patterns and gene expression, and in some cases cause their overt tumorigenic conversion. Moreover, EVs circulating in blood and present in body fluids provide an unprecedented access to the molecular circuitry driving cancer cells, and new technologies are being developed to exploit this property as a source of unique cancer biomarkers. (shrink)

Mary Midgley challenges the dominant conceptions of human nature, ethics, community and ecology taught at A-Level. This article considers some of the key themes of her thinking.

This article investigates the question concerning moral deskilling in the context of autonomous weapon systems. To this end, it interrogates the appropriateness of deskilling as an analytical tool, the consequences of the conflation of the terms “the warrior” and “the soldier,” and the impact of the dominant, but commonplace, understanding of autonomous weapons that underwrites the concerns that have been expressed thus far. While affirming the critical importance of the question regarding moral deskilling in the context of advanced weapons and (...) technologies, this article argues (a) that the notion of deskilling may not be an adequate or even appropriate analytical tool to investigate the matter on hand; (b) that the conflation of the terms “the warrior” and “the soldier” only serves to obfuscate the critical issues at stake; and (c) that the understanding of autonomous weapons that underwrites the concern is highly speculative. To this extent, the concern regarding moral deskilling in the context of autonomous weapon systems is ill-served. By way of a conclusion, the article calls for a more careful and nuanced approach and makes some preliminary suggestions as to how the question regarding moral deskilling in the context of autonomous weapon systems may be addressed. (shrink)